Irvine, D. Data Availability: All relevant data are within the paper and its Supporting Information files. Abstract The predictive value of sperm motility parameters obtained by computer-assisted semen analysis CASA was evaluated for the fertility of men from general population. Morphology, the most subjective marker, was also assessed in our study as higher using CASA, with significantly higher standard deviation values th an in the manual analysi s. One possible effect is an adverse influence on the quality of semen, which has been linked or at least discussed for a number of work place related substances — e. This appears to be the first study showing the value of CASA in prediction of fertility in the general male population.
Computer-assisted sperm analysis (CASA): capabilities and potential developments.
Semen analysis - Wikipedia
CASA might offer a chance to improve the repeatability and objectivity of sperm parameter s. The semen samples were collected and recorded on videotapes for CASA analysis in both Copenhagen and Aarhus, and the same recording protocols were applied in the two centres except of the sample volume pipetted into Makler chamber being 2. More on this topic Time to pregnancy in relation to semen quality assessed by CASA before and after sperm separation. Figure 2. CASA was made on semen samples collected at start of the enrolment, and the analysis is based on samples from men of the men included in the whole study. For the Bland-Altman test, the difference vs. Under experimental conditions, when a control situation is compared with another using a putative chemoattractant agent, a chemotaxis phenomenon is assumed to exist if the O.
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In order to confirm the correct functioning of the module, we also performed a bootstrapping analysis. They found that with time the values assessed with both methods became similar, which might prove the importance of training and experience with the automatic system when the final result is concerned. Thus, open-source software has been used for morphometry [ 5 ], motility [ 16 — 18 ] and membrane integrity [ 19 ] analysis. The predictive value of sperm motility parameters obtained by computer-assisted semen analysis CASA was evaluated for the fertility of men from general population. This finding is in agreement with recently published results of manually determined sperm concentration assessment based on the same population material Bonde et al.
We have tried to follow the good practices for computational science proposed by other authors [ 23 , 24 ], and thus the source code has been structured in different packages depending on its functionality. Aitken, R. The histogram comes from O. Next article sexy blonde celebrities nude